This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. It is suggested that NIVCD may be associated with future occurrence of atrial fibrillation in patients with structurally normal heart and sinus rhythm. Third, among patients with structurally normal heart and sinus rhythm, those with NIVCD had a higher risk for Conclusions Second, among patients with structurally normal heart and sinus rhythm, those with NIVCD were more likely to have slow sinus rate and prolonged PR interval than those with normal QRS complex. The main findings of this study are as follows: First, in the total study population, patients with NIVCD were more likely to be male and have preexisting AF than patients with normal QRS complex. In the unmatched cohort, the frequencies of male sex, preexisting AF, mitral regurgitation, and first-degree AVB were significantly higher in the NIVCD group than in the normal QRS group. Table 1 and supplementary table 1 summarize the baseline characteristics, medication histories, and ECG parameters in the unmatched and matched cohorts. After applying propensity score matching, continuous and categorical variables were compared using paired-sample Results For unmatched data, continuous and categorical variables were compared using independent-sample t-test and Pearson's χ 2 test, respectively. To avoid potential confounders, we used propensity score matching for the creation of the matched cohort from the unmatched cohort. The institutional review board waived both the need for the acquisition of informed consent from patients to be included in the analysis and the need for review by a critical event committee owing to the study's retrospective nature and the absence of patient identification data presented.Ĭontinuous data are expressed as mean ± standard deviation, whereas categorical data are presented as numbers (%). The study design was approved by the institutional review board (IRB number: 4-2018-1105), the study was conducted in accordance with the Declaration of Helsinki. This study was a retrospective cohort study. In the general population, left bundle branch block is Materials and methods The long-term prognosis of left and right bundle branch block is relatively well known. IVCD comprises three–namely, left bundle branch block, right bundle branch block, and nonspecific IVCD (NIVCD).

Widening of the QRS complex results from intraventricular conduction delay (IVCD) and is associated with cardiovascular mortality in the general population. At baseline, 1,789 (15.1%) patients had left bundle branch block (LBBB), 524 (4.4%) RBBB, 454 (3.8%) non-specific IVCD, 2588 (21.8%) 'mildly abnormal' QRS (110-129 milliseconds ) and 6506 (54.The QRS complex on electrocardiogram (ECG) reflects ventricular depolarization. Methods and results: Risk of the primary composite outcome of cardiovascular death or HF hospitalization and all-cause mortality were estimated by use of Cox regression according to baseline QRS duration and morphology in 11,861 patients without an intracardiac device. We addressed these questions in the PARADIGM-HF and ATMOSPHERE trials. Aims: The importance of intraventricular conduction delay (IVCD), incidence of new IVCD and its relationship to outcomes in heart failure and reduced ejection fraction (HFrEF) is not well studied.

Ivcd intraventricular conduction delay